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We make targeted investments in highly qualified people to maintain a strong focus on innovation and development.

We believe that molecular diagnostic kits are essential to providing everyone with access to effective, affordable and personalized medicine.

September 25th, 2016 - September 29th, 2016 | Cologne, Germany | XXXI International Congress of the International Academy of Pathology and the 28th Congress of the European Society of Pathology

Multiplicom...

believes that molecular diagnostic kits are essential to providing everyone with access to effective, affordable and personalized medicine.

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News & Press

September 16th, 2016

Acta Medica - Carrier molecules and extraction of circulating tumor DNA for next generation sequencing in colorectal cancer.

For plasma ctDNA extraction, the following carriers were tested: carrier RNA, polyadenylic acid, glycogen, linear acrylamide, yeast tRNA, salmon sperm DNA, and herring sperm DNA. Each extract was characterized by quantitative real-time PCR and next generation sequencing. The addition of polyadenylic acid had a significant positive effect on the amount of ctDNA eluted. The sequencing data revealed five cases of ctDNA mutated in KRAS and one patient with a BRAF mutation. An agreement of 86 % was found between tumor tissues and ctDNA.

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September 14th, 2016

Clarigo receives first prize in “innovative Medical Service” category in Greece

Athens University Professor Pantelis Konstantoulakis, a Molecular Biologist & Geneticist, accepted the award on behalf of Science Labs. “In these financially challenging times for our country, healthcare services offered to fellow citizens should not be underperforming and we should not go back to those days when we were just watching the scientific progress made in other “developed” countries.

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September 14th, 2016

Dailyhellas.com - Clarigo Prenatal Test gets first prize in “innovative Medical Service” category

Non-Invasive Prenatal Testing (NIPT), based on a fully certified technique (ClarigoTM), received a golden award during yesterday’s Healthcare Business Awards ceremony. All award-winners were announced and all best practices from the entire Healthcare spectrum were presented during the event.

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September 6th, 2016

Journal of Medical Genetics: Homozygous and compound heterozygous mutations in the FBN1 gene: unexpected findings in molecular diagnosis of Marfan syndrome

Methods and results: In the context of molecular diagnosis of heterozygous MFS, systematic sequencing of the FBN1 gene was performed in 2500 probands referred nationwide. 1400 probands carried a heterozygous mutation in this gene. Unexpectedly, among them four homozygous cases (0.29%) and five compound heterozygous cases (0.36%) were identified (total: 0.64%). Interestingly, none of these cases carried two premature termination codon mutations in the FBN1 gene.

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September 5th, 2016

Multiplicom nominated for the award ‘Promising Company of the Year 2016’

EY nominated Multiplicom for the award of ‘Promising Company of the Year 2016’. This title is awarded by the Flemish government to companies who show clear growth potential. The nominees are all fast-growing enterprises in a development phase.

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August 22nd, 2016

European Journal of Human Genetics: New challenges for BRCA testing: a view from the diagnostic laboratory

Many diagnostic laboratories are adopting next-generation sequencing (NGS) technology to increase their screening capacity and reduce processing time and unit costs. However, migration to NGS introduces complexities arising from choice of components of the BRCA testing workflow, such as NGS platform, enrichment method and bioinformatics analysis process. An efficient, cost-effective accurate mutation detection strategy and a standardised, systematic approach to the reporting of BRCA test results is imperative for diagnostic laboratories.

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August 17th, 2016

Research article: Analysis of Founder Mutations in Rare Tumors Associated With Hereditary Breast/ Ovarian Cancer Reveals a Novel Association of BRCA2 Mutations with Ampulla of Vater Carcinomas

A total of 102 male breast, 68 pancreatic and 33 peritoneal/fallopian tube carcinoma cases were included in the study. The BRCA2 c.156_157insAlu mutation was observed with a frequency of 7.8% in male breast cancers, 3.0% in peritoneal/fallopian tube cancers, and 1.6% in pancreatic cancers, with estimated total contributions of germline BRCA2 mutations of 14.3%, 5.5%, and 2.8%, respectively. No carriers of the BRCA1 c.3331_3334del mutation were identified.

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August 15th, 2016

AACR Publications: Validation of a MEK/MET-specific NGS panel for early phase trial interrogation

After combining well-established quality metrics to cover pre-analytical aspects with suitable technologies such as the MiSeq platform (Illumina) and appropriate bioinformatics, we recognize that this MEK/MET-specific NGS panel is fit for purpose.

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August 11th, 2016

Biovox - How to invest in Biotech - Rudi Mariën

"The current biotech landscape is full of interesting companies with a lot of potential. A great example is Multiplicom. They are doing a really good job with their genetic testing kits; they developed a BRCA test for detecting breast cancer – 1 in 2 labs uses their kits – and they just launched their line of NIPT prenatal tests. There's a good team in charge and the company has products on the market. This is an excellent position for a company to be in!"(...)

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Events

September 25th, 2016 - September 29th, 2016 | Cologne, Germany

XXXI International Congress of the International Academy of Pathology and the 28th Congress of the European Society of Pathology

The XXXI International Congress of the International Academy of Pathology and the 28th Congress of the European Society of Pathology will for the first time be organized as a joint venture. The motto of the Congress – Predictive Pathology, Guiding and Monitoring Therapy – indicates the future role of pathology as a strong partner for the different clinical specialties. The scientific programme will include science, translational research and clinical application to provide delegates with information on recent research findings, new technologies and up to date education.

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September 25th, 2016 - September 28th, 2016 | Wynn, Las Vegas

CAP16

Multiplicom goes to Vegas! We would like to welcome you during the CAP16 at our booth n° 717 to meet our local representative Bruce Simmons. At the CAP16 Annual Meeting, you can:

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September 29th, 2016 - October 1st, 2016 | Salzburg, Austria

Joint Swiss and Austrian Senology Symposium 2016

Join us for the Joint Swiss and Austrian Senology Symposium in Salzburg from 29 September until 1 October 2016 at our booth and meet our local representative Silvia Dorn.

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October 6th, 2016 - October 6th, 2016 | Amsterdam, The Netherlands

NVHG Autumn Symposium 2016

Multiplicom is happy to invite you to its booth during the NVHG Autumn Symposium 2016 in Amsterdam on 6 October 2016. Learn more about Multiplicom’s human genetic solutions by making an appointment with our local representative, Peter Van Hauwe.

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October 7th, 2016 - October 9th, 2016 | Berlin, Germany

16. Bundeskongress Pathologie

This conference, organized by the Bundesverband Deutscher Pathologen (BVDP) and the DVTA brings German pathologists, biologists, technicians and analysts together. This year’s congress treats the future of pathology and gives practical examples.Visit the website for the full programme.    

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October 7th, 2016 - October 11th, 2016 | Copenhagen, Denmark

ESMO 2016 Congress – from disease treatment to patient care

Don’t hesitate to visit our poster number 1174P on NRAS, KRAS and BRAF mutations in FFPE derived DNA or to contact us for further questions or explanation.

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October 7th, 2016 - October 8th, 2016 | Potsdam, Germany

The Annual AGD Meeting 2016

From 7-8 October 2016, Multiplicom will be sponsoring the annual AGD Meeting 2016. Come and visit us at our booth, or make an appointment with our local representative, Roel Reinders.

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October 11th, 2016 - October 14th, 2016 | Belgium

Clarigo workshop October

Multiplicom organizes workshops to help diagnostic centers implement Clarigo efficiently in their own laboratory facilities. The Clarigo workshop is intended to provide hands-on lab training of the complete Clarigo workflow and is therefore of particular interest to the person in charge of practical implementation or lab technicians. The workshop will span 4 days (Tuesday 2PM - Friday 2PM).

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October 12th, 2016 - October 15th, 2016 | Ghent, Belgium

7th Belgian Week of Pathology

Pathology is currently undergoing important changes, and this evolution in this field has impact on medical decisions in daily practice. This prompted the organization of the BWP to develop an up-to-date scientific program, accessible for experienced pathologists as well as for trainees and other young colleagues. Internationally renowned experts and leading Belgian pathologists, molecular biologists and clinicians will share their insights in a constructive and friendly atmosphere.

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